CKD-516

CAT: 1410-M10645-03Size: 50 mgDry Ice: NoHazardous: No

1 / 1

CAT#:1410-M10645-03Size:50 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

CKD-516 (Valecobulin, CKD516) is a potent beta-tubulin polymerization inhibitor with marked antitumor activity both in vitro and in vivo.

CAS Number

1188371-47-2

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

536.607

Molecular Formula

C26H28N6O5S

Notes

Research use only, not for human use.

Receptor

Microtubule/Tubulin

Chemical Information

CKD-516 free base

Valecobulin is a small molecule drug. Valecobulin has a monoisotopic molecular weight of 536.18 Da.

CAS Number	1188371-47-2
PubChem CID	44243402
IUPAC Name	(2S)-2-amino-3-methyl-N-[4-[3-(1,2,4-triazol-1-yl)-4-(3,4,5-trimethoxybenzoyl)phenyl]-1,3-thiazol-2-yl]butanamide
Molecular Formula	C26H28N6O5S
Molecular Weight	536.6
XLogP	3.6
Topological Polar Surface Area	172
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	10
Heavy Atom Count	38
Formal Charge	0
Complexity	794

SMILES

CC(C)[C@@H](C(=O)NC1=NC(=CS1)C2=CC(=C(C=C2)C(=O)C3=CC(=C(C(=C3)OC)OC)OC)N4C=NC=N4)N

InChI

InChI=1S/C26H28N6O5S/c1-14(2)22(27)25(34)31-26-30-18(11-38-26)15-6-7-17(19(8-15)32-13-28-12-29-32)23(33)16-9-20(35-3)24(37-5)21(10-16)36-4/h6-14,22H,27H2,1-5H3,(H,30,31,34)/t22-/m0/s1

InChIKey

UKKRUIXIDCWALA-QFIPXVFZSA-N

Chemical Structure

2D Structure

CAS: 1188371-47-2

CID: 44243402

Formula: C26H28N6O5S

MW: 536.6

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	536.6
XLogP3	3.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	10
Exact Mass	536.18418919
Monoisotopic Mass	536.18418919
Topological Polar Surface Area	172 Å²
Heavy Atom Count	38
Formal Charge	0
Complexity	794
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
M11682-01	CKD-519
M17690-01	UNBS-5162
M26124-01	CNS-5161 hydrochloride

Alternative Products

Catalog	Name
MBS3600645-01	CKD-516
HY-114214	CKD-712
T14976-01	CKD-519
HY-105291	CKD-711
GTR19274246-01	CKD-731
T36700-01	CKD 602
A18873-50	CKD-519 50mg
A18873-25	CKD-519 25mg
A18873-100	CKD-519 100mg
A18873-5	CKD-519 5mg

CKD-516

Chemical Information

Related Products

Alternative Products

Popular Products