Dacomitinib

• Description:

  Dacomitinib (PF-00299804, PF-299804) is a potent, irreversible, orally active pan-ErbB receptor tyrosine kinase inhibitor with IC50 of 6, 45.7 and 73.7 for EGFR, ERBB2 and ERBB4, respectively.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  469.9

• Molecular Formula:

  C24H25ClFN5O2

• Notes:

  Research use only, not for human use.

• Receptor:

  EGFR|HER2/ErbB2

• CAS Number:

  1110813-31-4