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CYC065

CAT: 1410-M10291-04Size: 10 mgDry Ice: NoHazardous: No
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CAT#:1410-M10291-04Size:10 mg
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Description
CYC065 is a derivative of seliciclib and second generation CDK inhibitor that is mainly active on CDK2/5/9.
CAS Number
1070790-89-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
397.527
Molecular Formula
C21H31N7O
Notes
Research use only, not for human use.
Receptor
CDK

Chemical Information

Fadraciclib

CYC-065 is under investigation in clinical trial NCT03739554 (CYC065 CDK Inhibitor and Venetoclax Study in Relapsed/Refractory CLL).

CAS Number1070790-89-4
PubChem CID24983461
IUPAC Name(2R,3S)-3-[[6-[(4,6-dimethyl-3-pyridinyl)methylamino]-9-propan-2-ylpurin-2-yl]amino]pentan-2-ol
Molecular FormulaC21H31N7O
Molecular Weight397.5
XLogP3.3
Topological Polar Surface Area101
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count8
Heavy Atom Count29
Formal Charge0
Complexity507
SMILES
CC[C@@H]([C@@H](C)O)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CN=C(C=C3C)C
InChI
InChI=1S/C21H31N7O/c1-7-17(15(6)29)25-21-26-19(18-20(27-21)28(11-24-18)12(2)3)23-10-16-9-22-14(5)8-13(16)4/h8-9,11-12,15,17,29H,7,10H2,1-6H3,(H2,23,25,26,27)/t15-,17+/m1/s1
InChIKey
DLPIYBKBHMZCJI-WBVHZDCISA-N
Chemical Structure
2D Structure
2D structure of Fadraciclib
CAS: 1070790-89-4
CID: 24983461
Formula: C21H31N7O
MW: 397.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight397.5
XLogP33.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count8
Exact Mass397.25900864
Monoisotopic Mass397.25900864
Topological Polar Surface Area101 Ų
Heavy Atom Count29
Formal Charge0
Complexity507
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BC175840-01CYC065
S7371-25mgFadraciclib (CYC065)
A20512-200CYC065 200mg
A20512-50CYC065 50mg
A20512-25CYC065 25mg
A20512-10CYC065 10mg
A20512-100CYC065 100mg
A20512-5CYC065 5mg
A20512-1CYC065 1mg
A20512-10mM-DCYC065 10mM * 1mL in DMSO

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