GDC-0980

• Description:

  GDC-0980 (Apitolisib, GNE 390, RG 7422) is a potent, selective, orally available class I PI3K/mTOR inhibitor with IC50 of 5 nM/27 nM/7 nM/14 nM for PI3Kα/β/δ/γ, inhibits mTOR inhibitor with Ki of 17 nM.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  498.6011

• Molecular Formula:

  C23H30N8O3S

• Notes:

  Research use only, not for human use.

• Receptor:

  MTOR|p110α|p110β|p110γ|p110δ

• CAS Number:

  1032754-93-0