4-CMTB

• Description :

  4-CMTB is a selective free fatty acid receptor 2 (FFA2/GPR43) agonist and a positive allosteric modulator (pEC50=6.38) [1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H319

• Target :

  Free Fatty Acid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/4-cmtb.html

• Purity :

  99.66

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(NC1=NC=CS1)C(C(C)C)C2=CC=C(Cl)C=C2

• Molecular Formula :

  C14H15ClN2OS

• Molecular Weight :

  294.80

• Precautions :

  H302, H319

• References & Citations :

  [1]Smith NJ, et al. Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator. Mol Pharmacol. 2011;80 (1) :163-173.|[2]Milligan G, Stoddart LA, Smith NJ. Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3. Br J Pharmacol. 2009;158 (1) :146-153.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [300851-67-6]