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4-CMTB

CAT: 0804-HY-P1125-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1125-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4-CMTB is a selective free fatty acid receptor 2 (FFA2/GPR43) agonist and a positive allosteric modulator (pEC50=6.38) [1].
CAS Number
300851-67-6
UNSPSC
12352005
Hazard Statement
H302, H319
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/4-cmtb.html
Purity
99.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=NC=CS1)C(C(C)C)C2=CC=C(Cl)C=C2
Molecular Formula
C14H15ClN2OS
Molecular Weight
294.80
Precautions
H302, H319
References & Citations
[1]Smith NJ, et al. Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator. Mol Pharmacol. 2011;80 (1) :163-173.|[2]Milligan G, Stoddart LA, Smith NJ. Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3. Br J Pharmacol. 2009;158 (1) :146-153.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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