MAT2A inhibitor 6

MAT2A inhibitor 6

• CAS Number: 2447686-21-5
• UNSPSC Description: MAT2A inhibitor 6 (Compound 3N-h) is a specific MAT2A inhibitor with oral activity and yellow fluorescence (IC50=26 nM), capable of visualizing MAT2A both in vitro and in vivo (λex = 430 nm, λem = 585 nm). MAT2A inhibitor 6 can induce apoptosis and has anticancer activity, which can be used in cancer research[1].
• Target Antigen: Apoptosis; Fluorescent Dye; Methionine Adenosyltransferase (MAT)
• Type: Dye Reagents
• Related Pathways: Apoptosis;Epigenetics;Metabolic Enzyme/Protease;Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mat2a-inhibitor-6.html
• Smiles: O=C1C(C2=CC=C(OC(F)F)C=C2)=C3C(C=CC(OCC)=N3)=NN1C4=CC5=CN(C)N=C5C=C4
• Molecular Weight: 463.44
• References & Citations: [1]Wang Z, et al. Computer-aided design of a fluorescent MAT2A inhibitor for visualized cancer synthetic lethality. Bioorg Chem. 2024 Sep;150:107582.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported