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ABP688

CAT: 0804-HY-110141-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-110141-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABP688 is a high affinity human mGluR5 antagonist with anKi of 1.7 nM. Radioisotope-labeled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5 receptor[1].
CAS Number
924298-51-1
UNSPSC
12352005
Hazard Statement
H228-H315-H319
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/abp688.html
Purity
98.02
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
CC1=NC(C#CC2=C/C(CCC2)=N/OC)=CC=C1
Molecular Formula
C15H16N2O
Molecular Weight
240.30
Precautions
P210-P240-P241-P264-P280-P302+P352-P305+P351+P338-P362+P364-P370+P378
References & Citations
[1]Hintermann S, et al. ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies. Bioorg Med Chem. 2007 Jan 15;15 (2) :903-14.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
MGluR5

Alternative Products

CatalogName
BA5575-25ABP688

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