Human Defensin B1 Recombinant Protein

• Background:

  Defensins are small cysteine-rich cationic proteins across cellular life, including vertebrate and invertebrate animals, plants, and fungi. They are host defense peptides, with members displaying either direct antimicrobial activity, immune signaling activities, or both. They are variously active against bacteria, fungi and many enveloped and nonenveloped viruses. They are typically 18-45 amino acids in length, with three or four highly conserved disulfide bonds. In animals, they are produced by cells of the innate immune system and epithelial cells, whereas in plants and fungi they are produced by a wide variety of tissues. An organism usually produces many different defensins, some of which are stored inside the cells (e.g. in neutrophil granulocytes to kill phagocytosed bacteria), and others are secreted into the extracellular medium. For those that directly kill microbes, their mechanism of action varies from disruption of the microbial cell membrane to metabolic disruption.

• Description:

  The Human Defensin B1 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Human Defensin B1 applications are for cell culture, ELISA standard, and Western Blot Control. Human Defensin B1 yeast-derived recombinant protein can be purchased in multiple sizes. Human Defensin B1 Specifications: (Molecular Weight: 3.9 kDa) (Amino Acid Sequence: DHYNCVSSGG QCLYSACPIF TKIQGTCYRG KAKCCK (36) ) (Gene ID: 1672) . For research use only.

• Applications:

  Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control

• Homology:

  Homo sapiens (human), Pan troglodytes (chimpanzee)

• Storage Temperature:

  -20°C