Multi-species (Canine, Feline, Ferret, Mink) IL-11 Recombinant Protein

• Background:

  Interleukin 11 (IL-11 or adipogenesis inhibitory factor) is a member of the IL-6-type cytokine family, distinguished based on their use of the common co-receptor gp130. Signal specificity is provided by the IL-11Rα subunit which is expressed at high levels in fibroblasts and other stromal cells but not immune cells, unlike IL-6 receptors that are expressed at highest levels in immune cells and lowly expressed in stromal cells. IL-11 has been shown to regulate adipogenesis, osteoclastogenesis, neurogenesis and platelet maturation. Over-expression of IL-11 is associated with a variety of cancers and may provide a link between inflammation and cancer.

• Description:

  The Multi-species IL-11 (Canine, Feline, Ferret, Mink) yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Multi-species IL-11 (Canine, Feline, Ferret, Mink) applications are for cell culture, ELISA standard, and Western Blot Control. Multi-species IL-11 (Canine, Feline, Ferret, Mink) yeast-derived recombinant protein can be purchased in multiple sizes. Multi-species IL-11 (Canine, Feline, Ferret, Mink) Specifications: (Molecular Weight: 19.1 kDa) (Amino Acid Sequence: APGPPPGPPR ASPDPRAELD SAVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LFSYLRHVQW LRRAGGPSLR TLEPELGALQ ARLDRLLRRL QLLMSRLALP QAPPDPPAPP LAPPASAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL (179) ) (Gene ID: 101085086 (feline) ) . For research use only.

• Applications:

  Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control

• Homology:

  Acinonyx jubatus (cheetah), Ailuropoda melanoleuca (giant panda), Callorhinus ursinus (northern fur seal), Canis lupus dingo (dingo), Canis lupus familiaris (dog), Felis catus (domestic cat), Gulo gulo luscus (American wolverine), Leopardus geoffroyi (Geoffroy's cat), Lutra lutra (Eurasian river otter), Lynx canadensis (Canada lynx), Lynx rufus (bobcat), Mustela erminea (ermine), Mustela putorius furo (domestic ferret), Neogale vison (American mink), Odobenus rosmarus divergens (Pacific walrus), Panthera leo (lion), Panthera pardus (leopard), Panthera tigris (tiger), Panthera uncia (snow leopard), Puma concolor (puma), Puma yagouaroundi (jaguarundi), Vulpes vulpes (red fox), Zalophus californianus (California sea lion)

• Storage Temperature:

  -20°C