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Mouse IL-1 beta ELISA

CAT: 0908-DIY0949M-01Size: 1 Pack (10 Plates)Dry Ice: NoHazardous: No
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CAT#:0908-DIY0949M-01Size:1 Pack (10 Plates)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-1 beta is produced by activated macrophages, monocytes, and a subset of dentritic cells. This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The IL-1 family of cytokines encompasses eleven proteins that each share a similar β-barrel structure and bind to Ig-like receptors. Several of the well characterized members of the IL-1-like cytokines play key roles in the development and regulation of inflammation. IL-1α, IL-1β, and IL-18 (IL-1F4) are well-known inflammatory cytokines active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. In contrast, IL-1 receptor antagonist (IL-1ra; IL-1F3) and IL-36 receptor antagonist (IL-36ra; IL-1F5) reduce inflammation by blocking the binding of the agonist receptor ligands. IL-33 (IL-1F11) is thought to function as an 'alarmin' released following cell necrosis to alerting the immune system to tissue damage or stress. The biological properties of IL-37 (IL-1F7) are mainly those of down-regulating inflammation.
Description
The Mouse IL-1 beta ELISA contains capture antibody, standard, and detection antibody for development of a Mouse IL-1 beta ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. This allows for complete flexibility to provide optimal dynamic range and sensitivity based on your sample type. Alternate names include IL1B, IL-1, IL1-BETA, IL1F2, interleukin 1 beta, IL1beta. The quantities of components provided are not matched. Components may also be purchased separately. For research use only.
Homology
Mus musculus (house mouse)
Storage Temperature
2°C to 8°C or -20°C
Scientific Category
ELISA

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