Feline VEGF-A Polyclonal Antibody - Biotinylated

• Background:

  VEGF proteins stimulate vasculogenesis and angiogenesis. They are part of the system that restores the oxygen supply to tissues when blood circulation is inadequate. The normal function of VEGF proteins is to create new blood vessels during embryonic development, new blood vessels after injury, muscle following exercise, and new vessels (collateral circulation) to bypass blocked vessels. The VEGF family has six members, including VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and Placental Growth Factor (PGF) . Activity of VEGF-A, as its name implies, has been studied mostly on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g., stimulation monocyte/macrophage migration, neurons, cancer cells, kidney epithelial cells) . In vitro, VEGF-A has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF-A is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor (VPF) .

• Description:

  The Feline VEGF-A polyclonal antibody is labeled and has been qualified for use in ELISA applications. It is the detection antibody in the Kingfisher Biotech Feline VEGF-A ELISA. The Feline VEGF-A antibody was produced in rabbits and is antigen-affinity purified. This antibody has shown no cross-reactivity with rabbit, or zebrafish VEGF-A proteins. This antibody has shown moderate to strong cross-reactivity with bovine, canine, caprine, equine, cynomolgus monkey, human, mouse, ovine, rat, and swine VEGF-A proteins. For research use only.

• Host:

  Rabbit

• Label:

  Biotin

• Applications:

  ELISA, ELISpot, Flow Cytometry, Neutralization, Western Blot

• Purification:

  Antigen-affinity

• Homology:

  Acinonyx jubatus (cheetah), Felis catus (domestic cat), Leopardus geoffroyi (Geoffroy's cat), Lynx pardinus (Spanish lynx), Prionailurus bengalensis (leopard cat), Puma concolor (puma)

• Storage Temperature:

  2°C to 8°C

• Scientific Category:

  Antibody