Rabbit IL-21 Polyclonal Antibody

• Background:

  IL-21 is a member of the type I cytokine family, which includes IL-2 and IL-15. IL-21 signals through the common gamma-chain and a unique IL-21 receptor. The IL-21 receptor is expressed in cells lymphoid-lineage and regulates the proliferation and differentiation of T and B lymphocytes. Studies suggest that IL-21 is a key component of CD4 T cell help that is required for maintaining the CD8+ T cell responses and inducing B cell antibody response. IL-21 also promotes the development of Th17 and Tfh cells, modulates the cytotoxic activity and survival of NK and CD8+ T cells, and suppresses the maturation of dendritic cells. It is also implicated in the development of autoimmune disease and has antitumor activity.

• Description:

  The Rabbit IL-21 polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Rabbit IL-21 ELISA. The Rabbit IL-21 antibody was produced in chickens and is antigen-affinity purified. The reactivity by species is: (Atlantic Salmon IL-21 - None) (Bovine IL-21 - None) (Canine IL-21 - None) (Chicken IL-21 - None) (Rabbit IL-21 - Strong) (Ovine 21 - Weak) (Swine IL-21 - None) . For research use only.

• Host:

  Chicken

• Label:

  Unconjugated

• Applications:

  ELISA, ELISpot, Flow Cytometry, Neutralization, Western Blot

• Purification:

  Antigen-affinity

• Homology:

  Oryctolagus cuniculus (rabbit)

• Storage Temperature:

  2°C to 8°C

• Scientific Category:

  Antibody