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Rabbit IL-21 Polyclonal Antibody

CAT: 0908-KP1313U-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0908-KP1313U-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-21 is a member of the type I cytokine family, which includes IL-2 and IL-15. IL-21 signals through the common gamma-chain and a unique IL-21 receptor. The IL-21 receptor is expressed in cells lymphoid-lineage and regulates the proliferation and differentiation of T and B lymphocytes. Studies suggest that IL-21 is a key component of CD4 T cell help that is required for maintaining the CD8+ T cell responses and inducing B cell antibody response. IL-21 also promotes the development of Th17 and Tfh cells, modulates the cytotoxic activity and survival of NK and CD8+ T cells, and suppresses the maturation of dendritic cells. It is also implicated in the development of autoimmune disease and has antitumor activity.
Description
The Rabbit IL-21 polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Rabbit IL-21 ELISA. The Rabbit IL-21 antibody was produced in chickens and is antigen-affinity purified. The reactivity by species is: (Atlantic Salmon IL-21 - None) (Bovine IL-21 - None) (Canine IL-21 - None) (Chicken IL-21 - None) (Rabbit IL-21 - Strong) (Ovine 21 - Weak) (Swine IL-21 - None) . For research use only.
Host
Chicken
Label
Unconjugated
Applications
ELISA, ELISpot, Flow Cytometry, Neutralization, Western Blot
Purification
Antigen-affinity
Homology
Oryctolagus cuniculus (rabbit)
Storage Temperature
2°C to 8°C
Scientific Category
Antibody

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