Equine IL-13 Polyclonal Antibody

• Background:

  IL-13 is secreted by many cell types, but especially T helper type 2 (Th2) cells. IL-13 is an important mediator of allergic inflammation and disease. In addition to effects on immune cells, IL-13 is implicated as a central mediator of the physiologic changes induced by allergic inflammation in many tissues. The functions of IL-13 overlap considerably with those of IL-4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL-4. Thus, although IL-13 can induce immunoglobulin E (IgE) secretion from activated human B cells, deletion of IL-13 from mice does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens.

• Description:

  The Equine IL-13 polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Equine IL-13 ELISA. The Equine IL-13 antibody was produced in rabbits and is antigen-affinity purified. The reactivity by species is: (Bovine IL-13 - None) (Canine IL-13 - None) (Caprine IL-13 - None) (Chicken IL-13 - None) (Dolphin IL-13 - Weak) (Equine IL-13 - Strong) (Human IL-13 - None) (Mouse IL-13 - None) (Ovine IL-13 - None) (Rabbit IL-13 - None) (Swine IL-13 - None) (Zebrafish IL-13 - None) . For research use only.

• Host:

  Rabbit

• Label:

  Unconjugated

• Applications:

  ELISA, ELISpot, Flow Cytometry, Neutralization, Western Blot

• Purification:

  Antigen-affinity

• Homology:

  Equus asinus (ass), Equus caballus (horse), Equus przewalskii (Przewalski's horse), Equus quagga (Plains Zebra)

• Storage Temperature:

  2°C to 8°C

• Scientific Category:

  Antibody