Equine IFN gamma Polyclonal Antibody

• Background:

  IFN gamma is a dimerized soluble cytokine that is the only member of the type II class of interferons. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-γ belongs. IFN-γ is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-γ expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-γ in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects. IFN-γ is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.

• Description:

  The Equine IFN gamma polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. The Equine IFN gamma polyclonal antibody was produced in rabbits and is antigen-affinity purified. The reactivity by species is: (Bovine IFN-gamma - Weak) (Canine IFN-gamma - Moderate) (Chicken IFN-gamma - None) (Dolphin IFN-gamma - Moderate) (Equine IFN-gamma - Strong) (Feline IFN-gamma - Weak) (Human IFN-gamma - Moderate) (Mouse IFN-gamma - Weak) (Rabbit IFN-gamma - Weak) (Swine IFN-gamma - Weak) . For research use only.

• Host:

  Rabbit

• Label:

  Unconjugated

• Applications:

  ELISA, ELISpot, Flow Cytometry, Neutralization, Western Blot

• Purification:

  Antigen-affinity

• Homology:

  Equus caballus (horse)

• Storage Temperature:

  2°C to 8°C

• Scientific Category:

  Antibody