UBA3 Rabbit mAb

• Background :

  Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.

• Description :

  This is a UBA3 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  HUba3; NEDD8 activating enzyme E1C; uba3; UBE1C

• Swiss Prot :

  Q8TBC4

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthesized peptide derived from human UBA3

• Clonality :

  Monoclonal

• Conjugation :

  Unconjugated

• Type :

  Recombinant Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Dilution :

  WB 1:500-1:2000

• Buffer :

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG