LEF1 Rabbit mAb

• Background :

  Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity) .

• Description :

  This is a LEF1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  LEF1_HUMAN; Lymphoid enhancer binding factor 1; TCF1 alpha; TCF10; Transcription factor T cell specific 1 alpha; TCF7L3

• Swiss Prot :

  Q9UJU2

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthesized peptide derived from human LEF1

• Clonality :

  Monoclonal

• Conjugation :

  Unconjugated

• Type :

  Recombinant Antibody

• Applications :

  WB, IHC, ICC/IF, IP, FC

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Dilution :

  WB 1:1000-1:2000, IHC 1:50-1:200, ICC/IF 1:100-1:500, IP 1:50, FC 1:50

• Buffer :

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG