LRP1 Rabbit mAb

• Background:

  Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.Functions as a receptor for Pseudomonas aeruginosa exotoxin A.

• Description:

  This is a LRP1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  A2MR; alpha 2MR; Alpha 2 macroglobulin receptor; CD91; APR; LRP1; LRP85; TGFBR5

• Swiss Prot:

  Q07954

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human LRP1

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, IHC, ICC/IF, IP, FC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Dilution:

  WB 1:10000-1:20000, IHC 1:50-1:100, ICC/IF 1:50-1:100, IP 1:30, FC 1:50

• Buffer:

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG