Vinculin Rabbit mAb

• Background :

  Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development. Three structural vinculin domains include an amino-terminal head, a short, flexible proline-rich region and a carboxy-terminal tail. In the inactive state, the head and tail domains of vinculin interact to form a closed confirmation. The open and active form of vinculin translocates to focal adhesions where it is thought to be involved in anchoring F-actin to the membrane and regulation of cell migration.

• Description :

  This is a Vinculin Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  Vinculin; VCL; Metavinculin; MV

• Swiss Prot :

  P18206

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthesized peptide derived from human Vinculin

• Clonality :

  Monoclonal

• Conjugation :

  Unconjugated

• Type :

  Recombinant Antibody

• Applications :

  WB, ICC/IF, IP

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Dilution :

  WB 1:10000-1:20000, ICC/IF 1:50-1:200, IP 1:50

• Buffer :

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG