Vinculin Rabbit mAb

• Background:

  Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development. Three structural vinculin domains include an amino-terminal head, a short, flexible proline-rich region and a carboxy-terminal tail. In the inactive state, the head and tail domains of vinculin interact to form a closed confirmation. The open and active form of vinculin translocates to focal adhesions where it is thought to be involved in anchoring F-actin to the membrane and regulation of cell migration.

• Description:

  This is a Vinculin Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Vinculin; VCL; Metavinculin; MV

• Swiss Prot:

  P18206

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human Vinculin

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, ICC/IF, IP

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Dilution:

  WB 1:10000-1:20000, ICC/IF 1:50-1:200, IP 1:50

• Buffer:

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG