PHD3 Rabbit mAb

• Background :

  Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

• Description :

  This is a PHD3 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  Egl nine homolog 3; EGLN3; Factor responsive smooth muscle protein; HIF Prolyl Hydroxylase 3; HIFP4H3; HIFPH3; P4H3; PHD3; SM20

• Swiss Prot :

  Q9H6Z9

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthesized peptide derived from human PHD3

• Clonality :

  Monoclonal

• Conjugation :

  Unconjugated

• Type :

  Recombinant Antibody

• Applications :

  WB, ICC/IF, IP

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Dilution :

  WB 1:500-1:2000, ICC/IF 1:50-1:200, IP 1:50

• Buffer :

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  27kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG