CD133 Rabbit mAb

• Background :

  May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617) . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

• Description :

  This is a CD133 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  AC133; CD133; CORD12; hProminin; MCDR2; PROM1; Prominin like 1; Prominin1; PROML1; RP41; STGD4

• Swiss Prot :

  O43490

• Reactivity :

  Human

• Immunogen :

  A synthesized peptide derived from human CD133

• Clonality :

  Monoclonal

• Conjugation :

  Unconjugated

• Type :

  Recombinant Antibody

• Applications :

  WB, IHC

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Dilution :

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer :

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  133kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG