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TRIM25 Rabbit mAb

CAT: 0866-RDSA65529Size: 100 µLDry Ice: NoHazardous: No
CAT#:0866-RDSA65529Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.
Description
This is a TRIM25 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
EFP; RNF147; TRI25; TRIM 25; Trim25; Z147; ZNF147
Swiss Prot
Q14258
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human TRIM25
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200, ICC/IF 1:100-1:500, IP 1:50, FC 1:60
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
71kDa
Host or Source
Rabbit
Isotype
IgG

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