TRIM25 Rabbit mAb

• Background:

  Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.

• Description:

  This is a TRIM25 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  EFP; RNF147; TRI25; TRIM 25; Trim25; Z147; ZNF147

• Swiss Prot:

  Q14258

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human TRIM25

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, IHC, ICC/IF, IP, FC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Dilution:

  WB 1:1000-1:5000, IHC 1:50-1:200, ICC/IF 1:100-1:500, IP 1:50, FC 1:60

• Buffer:

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  71kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG