RAP80 Rabbit mAb

• Background :

  Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs) .

• Description :

  This is a RAP80 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  BRCA1-A complex subunit RAP80; RAP80; Receptor associated protein 80; RIP110; Rxrip110; UIMC1; X2HRIP110

• Swiss Prot :

  Q96RL1

• Reactivity :

  Human

• Immunogen :

  A synthesized peptide derived from human RAP80

• Clonality :

  Monoclonal

• Conjugation :

  Unconjugated

• Type :

  Recombinant Antibody

• Applications :

  WB, IHC, ICC/IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Dilution :

  WB 1:1000-1:5000, IHC 1:50-1:200, ICC/IF 1:50-1:200

• Buffer :

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  80kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG