Menin Rabbit mAb

• Background:

  Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL) -containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes.

• Description:

  This is a Menin Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MEA1; Men1; Menin; Multiple Endocrine Adenomatosis 1; Multiple Endocrine Neoplasia 1; SCG2; Suppressor Candidate Gene 2; Wermer syndrome; ZES

• Swiss Prot:

  O00255

• Reactivity:

  Human

• Immunogen:

  A synthesized peptide derived from human Menin

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, IHC, ICC/IF, IP

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Dilution:

  WB 1:1000-1:5000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50

• Buffer:

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  68kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG