BACE1 Rabbit mAb

• Background:

  Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

• Description:

  This is a BACE1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Memapsin-2; BACE1; BACE

• Swiss Prot:

  P56817

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human BACE1

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, IP

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Dilution:

  WB 1:500-1:2000, IP 1:40

• Buffer:

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  70kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG