PUMA Rabbit mAb

• Background:

  Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.

• Description:

  This is a PUMA Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  BBC3; bcl2 binding component 3; jfy1; puma; p53 up-regulated modulator of apoptosis; PUMA alpha

• Swiss Prot:

  Q9BXH1

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human PUMA

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, IHC, ICC/IF, FC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, FC 1:50

• Buffer:

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  18kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG