Rad21 Rabbit mAb

• Background :

  Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic cleavage by separase, a caspaselike enzyme, allows chromosomal separation. Rad21 interacts with Rec8 to form a cohesin complex that functions in sister chromatid alignment. Rad21 is also involved in the repair of double-strand breaks in DNA and is essential for mitotic growth. Rad21 undergoes a C-terminal cleavage induced by diverse stimuli right before apoptosis.

• Description :

  This is a Rad21 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  HHR21; Nuclear matrix protein 1; NXP-1; SCC1 homolog; HR21; KIAA0078; NXP1; Rad21

• Swiss Prot :

  O60216

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthesized peptide derived from human Rad21

• Clonality :

  Monoclonal

• Conjugation :

  Unconjugated

• Type :

  Recombinant Antibody

• Applications :

  WB, FC

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Dilution :

  WB 1:500-1:1000, FC 1:50

• Buffer :

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  72,128kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG