Products for Research Use Only
RegisterLogin

LRRK2 Rabbit mAb

CAT: 0866-RDSA65269Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0866-RDSA65269Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
LRRK2 positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS) . Plays a role in synaptic vesicle trafficking. Phosphorylates PRDX3. Has GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease.
Description
This is a LRRK2 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Leucine-rich repeat serine/threonine-protein kinase 2; Dardarin; PARK8; ROCO2; RIPK7; LRRK2
Swiss Prot
Q5S007
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human LRRK2
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
286kDa
Host or Source
Rabbit
Isotype
IgG

Related Products

CatalogName
RDSA65082LRRK2 (Phospho-Ser935) Rabbit mAb
RD267089A-01LRRK2 Polyclonal Antibody
RDSA68214Β-Actin Rabbit mAb
RDSA68209IL12B Rabbit mAb
RDSA68206IL9 Rabbit mAb
RDSA68203HtrA1 Rabbit mAb
RDSA68198BCL2L15 Rabbit mAb
RDSA68196CBR1 Rabbit mAb
RDSA68195SOCS7 Rabbit mAb
RDSA68193NDUFAB1 Rabbit mAb

Alternative Products

CatalogName
GTR17691822Phospho-LRRK2/LRRK2 Rabbit Monoclonal Antibody
A22759-01LRRK2 Rabbit mAb
E45R17569NLRRK2 Rabbit pAb

Popular Products