Histone H2A.X (Phospho-Ser139) Rabbit mAb

• Background:

  Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

• Description:

  This is a Histone H2A.X (Phospho-Ser139) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X

• Swiss Prot:

  P16104

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human Phospho-Histone H2A.X (S139)

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, IHC, ICC/IF, IP

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Dilution:

  WB 1:5000-1:10000, IHC 1:50-1:200, ICC 1:50-1:200, IP 1:30

• Buffer:

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  15kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG