P53 (Phospho-Thr55) Rabbit mAb

• Background:

  Plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor.

• Description:

  This is a p53 (Phospho-Thr55) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Antigen NY-CO-13; TP53; Tumor suppressor p53; Cellular tumor antigen p53; Phosphoprotein p53

• Swiss Prot:

  P04637

• Reactivity:

  Human

• Immunogen:

  A synthesized peptide derived from human Phospho-p53 (T55)

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Dilution:

  WB 1:500-1:2000

• Buffer:

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  53kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG