Retinoblastoma (Phospho-Ser780) Rabbit mAb

• Background:

  Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.

• Description:

  This is a Retinoblastoma (Phospho-Ser780) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  OSRC; RB; p105-Rb; pRb; RB1; pp110; Retinoblastoma 1; PPP1R130

• Swiss Prot:

  P06400

• Reactivity:

  Human

• Immunogen:

  A synthesized peptide derived from human Retinoblastoma

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer:

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  110kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG