HP1γ (Phospho-Ser93) Antibody

• Background:

  At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

• Description:

  This is a HP1γ (Phospho-Ser93) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  HECH; HP1 gamma; HP1Hs-gamma; chromobox 3

• Gene ID:

  11335

• Swiss Prot:

  Q13185

• Reactivity:

  Human

• Immunogen:

  Peptide sequence around phosphorylation site of Serine 93 (R-L-S (p) -L-S) derived from Human HP1γ.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Phospho-Specific Antibody

• Applications:

  WB

• Purification Method:

  Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.

• Assay Type:

  Antibody

• Concentration:

  1.0 mg/mL

• Dilution:

  WB 1:500-1:1000

• Buffer:

  Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Observed Molecular Weight:

  24kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG