IRAK1 (Phospho-Ser376) Antibody

• Background:

  IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.

• Description:

  This is a IRAK1 (Phospho-Ser376) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  IL1RAK; IRAK; mPLK

• Gene ID:

  3654

• Swiss Prot:

  P51617

• Reactivity:

  Human

• Immunogen:

  Peptide sequence around phosphorylation site of Serine 376 (Q-S-S (p) -M-V) derived from Human IRAK1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Phospho-Specific Antibody

• Applications:

  IHC

• Purification Method:

  Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.

• Assay Type:

  Antibody

• Concentration:

  1.0 mg/mL

• Dilution:

  IHC 1:50-1:100

• Buffer:

  Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Observed Molecular Weight:

  76kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG