SHP-1 (Phospho-Tyr536) Antibody

• Background:

  Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.

• Description:

  This is a SHP-1 (Phospho-Tyr536) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  70Z-SHP; HCP; HCPH; Hematopoietic cell protein-tyrosine phosphatase; PTN6

• Gene ID:

  5777

• Swiss Prot:

  P29350

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Peptide sequence around phosphorylation site of tyrosine 536 (S-E-Y (p) -G-N) derived from Human SHP-1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Phospho-Specific Antibody

• Applications:

  WB, IHC, IF

• Purification Method:

  Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.

• Assay Type:

  Antibody

• Concentration:

  1.0 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:100-1:300 , IF 1:50-1:200

• Buffer:

  Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG