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ADAM17 Antibody

CAT: 0864-A76251-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0864-A76251-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Aliases
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b) , ADAM17, CSVP TACE
UniProt
P78536
Host
HEK293F Cell
Antigen Species
Human
Reactivity
Human
Target Antigen
A synthesized peptide derived from human ADAM17
Target
ADAM17
Clonality
Monoclonal
Conjugation
Non-conjugated
Field of Research
Neuroscience, Cancer, Cell biology, Metabolism, Signal transduction, Stem cells
Purification Method
Affinity chromatography
Form
Liquid
Buffer
PBS, 150mM NaCl, 0.02% sodium azide, 50% glycerol, pH 7.4.
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Fragment
Rabbit IgG

UniProtKB · P78536

Disintegrin and metalloproteinase domain-containing protein 17

ADA17_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P78536
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ADAM17
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ADAM 17
EC number
3.4.24.86
Processing
Precursor
Secondary accessions
O60226
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoproteinUbl conjugationZymogen

Disease

Disease variantHypotrichosis

Molecular function

HydrolaseMetalloproteaseProtease

Ligand

Metal-bindingZinc

Biological process

Notch signaling pathway

Domain

SH3-bindingSignalTransmembraneTransmembrane helix

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