1,2-Dihydropyridazine-3,6-dione-3,4,5,6-13C4

1,2-Dihydropyridazine-3,6-dione-3,4,5,6-13C4

• CAS Number: 2140327-62-2
• UNSPSC Description: 1,2-Dihydropyridazine-3,6-dione-3,4,5,6-13C4 (1,2-Dihydro-3,6-pyridazine-13C4-dione) is 13C labeled Maleic hydrazide. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins[1][2].
• Target Antigen: DNA/RNA Synthesis; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Cell Cycle/DNA Damage;Others
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/1-2-dihydropyridazine-3-6-dione-3-4-5-6-13c4.html
• Smiles: O=[13C]1[13CH]=[13CH][13C](NN1)=O
• Molecular Weight: 116.06
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Venezian A, et al. The Influence of the Plant Growth Regulator Maleic Hydrazide on Egyptian Broomrape Early Developmental Stages and Its Control Efficacy in Tomato under Greenhouse and Field Conditions. Front Plant Sci. 2017;8:691. Published 2017 May 16.|[3]Swietlińska Z, et al. Cytotoxic effects of maleic hydrazide. Mutat Res. 1978;55(1):15-30.|[4]Yurdakok B, et al. Cytotoxic effects of etephon and maleic hydrazide in Vero, Hep2, HepG2 cells. Drug Chem Toxicol. 2014;37(4):459-465.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported