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Desmethylnortriptyline

CAT: 0804-HY-100651-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100651-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Desmethylnortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline (HY-B0527), and is used to relieve the symptoms of depression[1][2].
CAS Number
4444-42-2
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/desmethylnortriptyline.html
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NCC/C=C1C2=CC=CC=C2CCC3=CC=CC=C\13
Molecular Formula
C18H19N
Molecular Weight
249.35
References & Citations
[1]Burch JE, et al. Determination of desmethyl nortriptyline in plasma by gas chromatography before and after treatment with salicylaldehyde. J Chromatogr. 1983 May 13;274:350-4.|[2]Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22 (4) :371-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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