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TDZD-8

CAT: 0127-BUP10327-02Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0127-BUP10327-02Size:10 mg
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CAS Number
327036-89-5
Synonyms
GSK-3ß Inhibitor I, NP 01139
Purity
=95%
Smiles
Cn1sc(=O)n(Cc2ccccc2)c1=O

Chemical Information

Tdzd-8

TDZD-8 is a member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a methyl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta). An experimental compound which was being developed for the potential treatment of Alzheimer's disease. It has a role as an antineoplastic agent, a neuroprotective agent, an anti-inflammatory agent, an apoptosis inducer and an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is a member of benzenes and a thiadiazolidine.

CAS Number327036-89-5
PubChem CID4124851
IUPAC Name4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
Molecular FormulaC10H10N2O2S
Molecular Weight222.27
XLogP1.5
Topological Polar Surface Area65.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Heavy Atom Count15
Formal Charge0
Complexity277
SMILES
CN1C(=O)N(C(=O)S1)CC2=CC=CC=C2
InChI
InChI=1S/C10H10N2O2S/c1-11-9(13)12(10(14)15-11)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3
InChIKey
JDSJDASOXWCHPN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Tdzd-8
CAS: 327036-89-5
CID: 4124851
Formula: C10H10N2O2S
MW: 222.27
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight222.27
XLogP31.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass222.04629874
Monoisotopic Mass222.04629874
Topological Polar Surface Area65.9 Ų
Heavy Atom Count15
Formal Charge0
Complexity277
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
B1249-5.1TDZD-8
FB18327-01TDZD 8

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