Products for Research Use Only
RegisterLogin

TPO

CAT: 0209-R20-058-L500Size: 500 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0209-R20-058-L500Size:500 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant rat TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein.
Synonyms
DDX4; VASA
NCBI Gene ID
54314
UniProt
P49745
Accession Number
NP_112395.1
Accession Number mRNA
NM_031133.2
Chromosomal Location
6q16
Reactivity
Rat
Cross Reactivity
Rat, Human
Sequence
SPVPPACDPR LLNKLLRDSY LLHSRLSQCP DVNPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPPQGRTTA HKDPSALFLS LQQLLRGKVR FLLLVEGPAL CVRRTLPTTA VPSRTSQLLT LNKF
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to stimulate the proliferation of human MO7e cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
Length
174
Form
Lyophilized
Molecular Weight
18.7 kDa
Host or Source
E. coli

Alternative Products

CatalogName
CN-A038-500GMAgar, Micropropagation - Type I (Gracilaria)
M2302-20HPhaseShield™ Gel Tubes, Heavy (200x 2ml)
M2302-20LPhaseShield™ Gel Tubes, Light (200x 2ml)
BCS81BioCoupler® Glass Set (8 oz) x1
RHD55901Anti-PTGS1 Antibody (R1S27)
E-EL-H1579ELISA kit for Human PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9)
EA-IP-017MProtein L Magnetic beads
RHD55804Anti-TCEA1 Antibody (R1S24)
E-EL-M2699ELISA kit for Mouse ACTN1 (Actinin Alpha 1)
RHD55803Anti-TCEA1 Antibody (R1S23)

Popular Products