MIP-1 gamma (CCL9/10)

• Description:

  MIP-1γ is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog. MIP-1γ signals through the CCR1 receptor. MIP-1γ chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1γ contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant murine MIP-1γ is an 11.6 kDa protein containing 101 amino acid residues.

• Synonyms:

  Ccl9; CCF18; MRP-2; Scya9; Scya10

• NCBI Gene ID:

  20308

• UniProt:

  P51670

• Accession Number:

  NP_035468.1

• Accession Number mRNA:

  NM_011338.2

• Chromosomal Location:

  11 C; 11 47.4 cM

• Reactivity:

  Mouse

• Cross Reactivity:

  Human

• Sequence:

  QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Determined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10.0 ng/ml.

• Length:

  101

• Form:

  Lyophilized

• Molecular Weight:

  11.6 kDa

• Host or Source:

  E. coli