Lymphotactin

• Description:

  Lymphotactin is the only known member of the C-chemokine family and signals through the receptor XCR1, formally known as GPR5. The spleen shows the highest level of lymphotactin compared to peripheral leukocytes, lung, colon and small intestine. Lymphotactin is chemotactic towards lymphocytes but not towards monocytes or neutrophils. Recombinant human Lymphotactin is a 10.0 kDa protein consisting of 92 amino acid residues.

• Synonyms:

  XCL1; LTN; ATAC; LPTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a

• NCBI Gene ID:

  6375

• UniProt:

  P47992

• Accession Number:

  NP_002986.1

• Accession Number mRNA:

  NM_002995

• Chromosomal Location:

  1q23

• Reactivity:

  Human

• Cross Reactivity:

  Mouse, Human, Hamster, Bacteria

• Sequence:

  GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFIT KRGLKVCADP QATWVRDVVR SMDRKSNTRN NMIQTKPTGT QQSTNTAVTL TG

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Determined by its ability to chemoattract human T cells using a concentration of 10.0-100.0 ng/ml.

• Length:

  92

• Form:

  Lyophilized

• Molecular Weight:

  10 kDa

• Host or Source:

  E. coli