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Lactogen, placental

CAT: 0209-500-037-L1000Size: 1000 µgDry Ice: NoHazardous: No
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CAT#:0209-500-037-L1000Size:1000 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recombinant ovine placental lactogen, one polypeptide chain containing 199 amino and an additional Ala at N-terminus acids and having a molecular mass of ~ 23 kDa, was purified by proprietary chromatographic techniques (see Sakal et al. J. Endocrinology (1997), 152, 317-327. Ovine PL is also capable of activating human and other heterologous GH receptors but not ruminat GH receptors.
Synonyms
Chorionic somatomammotropin hormone, Placental lactogen (PL)
NCBI Gene ID
443319
UniProt
P16038
Accession Number
NP_001009309.2
Accession Number mRNA
NM_001009309.4
Reactivity
Ovine
Cross Reactivity
Ovine
Sequence
AQHPPYCRNQPGKCQIPLQSLFDRATTVANYNSKLAGEMVNRFDEQYGQGINSESKVINCHTSSITTPNSKAEAINTEDKILFKLVISLLHSWDEPLHHAVTELANSKGTSPALLTKAQEIKEKAKVLVDGVEVIQKRIHPGEKNEPYPVWSEQSSLTSQDENVRRVAFYRLFHCLHRDSSKIYTYLRILKCRLTSCET
Assay Protocol
It is recommended to reconstitute the lyophilized oPL in sterile water or 0.4% NaHCO3 adjusted tp pH 8-9, not less than 100µg/ml, which can then be further diluted to other aqueous solutions, preferably in presence of carrier protein.
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 99.0% as determined by Gel filtration and SDS-PAGE gel.
Bioactivity
Recombinant oPL is fully biologically active as evidenced by inducing proliferation of Nb2 cells.
Length
199
Form
Lyophilized
Reconstitution
Water
Molecular Weight
23.0 kDa
Host or Source
E. coli
N Terminal Sequence
AQHPP

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