EGF

CAT: 0209-R20-072-L500Size: 500 µgDry Ice: NoHazardous: No
CAT#:0209-R20-072-L500Size:500 µg
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Description
EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor) . Recombinant rat EGF is a 6.2 kDa globular protein containing 54 amino acid residues including 3 intramolecular disulfide-bonds.
Synonyms
Epidermal growth factor, Urogastrone, URG
NCBI Gene ID
25313
UniProt
P07522
Accession Number
NP_036974.1
Accession Number mRNA
NM_012842.1
Chromosomal Location
2q42-q43
Reactivity
Rat
Cross Reactivity
Mouse, Rat
Sequence
MNSNTGCPPS YDGYCLNGGV CMYVESVDRY VCNCVIGYIG ERCQHRDLRW WKLR
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Length
54
Form
Lyophilized
Molecular Weight
6.2 kDa
Host or Source
E. coli

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