EGF

CAT: 0209-M10-003-L1000Size: 1000 µgDry Ice: NoHazardous: No
CAT#:0209-M10-003-L1000Size:1000 µg
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Description
Epidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor) . Recombinant murine EGF is a 6.0 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide-bonds.
Synonyms
Epidermal growth factor; Egf; AI790464
NCBI Gene ID
13645
UniProt
P01132
Accession Number
NP_034243.2
Accession Number mRNA
NM_010113.3
Chromosomal Location
3 G3; 3 65.2 cM
Reactivity
Mouse
Cross Reactivity
Human, Mouse, Rat
Sequence
NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Length
53
Form
Lyophilized
Molecular Weight
6.0 kDa
Host or Source
E. coli

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