Recombinant Phospho-CRMP2 (Thr514) Monoclonal Antibody

• Background:

  This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

• Abbreviation:

  Phospho-CRMP2 (Thr514)

• UniProt:

  Q16555

• Host:

  Rabbit

• Reactivity:

  Rat

• Immunogen:

  Phosphorylated human CRMP2 (Thr514) peptide

• Target:

  N2A; DPYSL; DHPRP; DRP; DPYSL2; CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2; dihydropyrimidinase like 2

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A793

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Neuroscience

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  63 kDa

• Observed Molecular Weight:

  60-80 kDa

• Isotype:

  IgG, κ