Recombinant CLEC2D Monoclonal Antibody

• Background:

  C-type lectin domain family 2 member D (CLEC2D), also known as lectin-like transcript 1 (LLT1) and osteoclast inhibitory lectin (OCIL), is a type II transmembrane C-type lectin receptor primarily expressed upon immune cell activation in T cells, B cells, NK cells, and plasmacytoid and monocyte-derived dendritic cells. CLEC2D interacts with NKR-P1A (KLRB1, CD161) on NK cells and some subsets of T cells, inhibiting NK cell cytotoxicity while alternatively inducing proliferation and IFNγ production in T cells. CLEC2D is also expressed by osteoblasts, inhibiting osteoclast formation and bone resorption.

• Abbreviation:

  CLEC2D

• UniProt:

  Q9UHP7

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant human CLEC2D fragment

• Target:

  LLT; CLEC2D; CLAX; LLT1; OCIL; C type lectin related f; C type lectin superfamily 2; CLC2D; CLEC2D protein; Clec2d5; C-type lectin domain family 2 member D; L LT1; Lectin like NK cell receptor; Lectin like transcript 1; Lectin-like NK cell receptor; Lectin-like transcript 1; LLT-1; member D; Osteoclast inhibitory lectin

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A686

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Immunology

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  22 kDa

• Observed Molecular Weight:

  25-35 kDa

• Isotype:

  IgG, κ