Recombinant IMPDH2 Monoclonal Antibody

• Background:

  Inosine-5'-monophosphate dehydrogenase 2, also known as IMP dehydrogenase 2, is an enzyme that in humans is encoded by the IMPDH2 gene.IMP dehydrogenase 2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. IMPDH2 catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 has been identified as an intracellular target of the natural product sanglifehrin A.

• Abbreviation:

  IMPDH2

• UniProt:

  P12268

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Recombinant human IMPDH2 fragment

• Target:

  IMPD; IMPDH; IMPDH2; IMPD2; IMPDH-II; IMDH2; IMP (inosine monophosphate) dehydrogenase 2; IMP dehydrogenase 2; IMP oxireductase 2; IMPD 2; IMPDH 2; IMPDH II; Inosine 5' monophosphate dehydrogenase 2; Inosine 5' phosphate dehydrogenase 2; Inosine monophosphate dehydrogenase type II; Inosine-5''-monophosphate dehydrogenase 2

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A264

• Conjugation:

  Unconjugated

• Applications:

  WB; IF; IP

• Field of Research:

  Signal Transduction; Cancer; Metabolism

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000; IF 1:50; IP 1:25-1:50

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  56 kDa

• Observed Molecular Weight:

  56 kDa

• Isotype:

  IgG, κ