Recombinant HLA-DPB1 Monoclonal Antibody

• Background:

  Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous.

• Abbreviation:

  HLA-DPB1

• UniProt:

  P04440

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Recombinant human HLA-DPB1 fragment

• Target:

  DPB; DP beta; DPB1; HLA-DP; HLA-DP1B; HLA-DPB; HLA-DPB1; major histocompatibility complex; class II; DP beta 1; beta-1 subunit; class I; D6S221E; DMA; DMB; DP beta 1 chain; DP (W4) beta chain; DPB 1; DRB; H2Ea; HLA class II histocompatibility antigen; HLA class II histocompatibility antigen DM beta chain; HLA DMB; HLA DP1A; HLA DPB1; HLA SB alpha chain; HLA-A; HLA-A histocompatibility type; HLADM; HLA-DP histocompatibility type; HLADP1B; HLASB; HLASB histocompatibility type; Human MHC class II HLA SB alpha; LA class II histocompatibility antigen DP alpha 1 chain; Major histocompatibility complex class II; Major histocompatibility complex class II DP alpha 1; Major histocompatibility complex class II DP beta 1; MHC class II antigen DMB; MHC class II antigen DPB1; MHC class II DP3 alpha; MHC class II DPA1; MHC class II HLA-DP-beta-1; MHC DPB1; MHC HLA DPB1; PLT1; Primed lymphocyte test 1; RING6; RING7

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A250

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC; IF; IP

• Field of Research:

  Immunology

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000; IHC 1:200-1:1000; IF 1:50; IP 1:50-1:100

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  29 kDa

• Observed Molecular Weight:

  29 kDa

• Isotype:

  IgG, κ