Recombinant Osteocalcin Monoclonal Antibody

• Background:

  This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.

• Abbreviation:

  Osteocalcin

• UniProt:

  P02818

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human Osteocalcin protein

• Target:

  PMF; BGLAP; BGP; OC; OCN; osteocalcin; PMF1; Bone gamma carboxyglutamate gla protein osteocalcin; Bone gamma carboxyglutamate protein; Bone Gamma-carboxyglutamate Protein; Gamma carboxyglutamic acid containing protein; OSTCN; OT; Bone Gla protein; Gamma-carboxyglutamic acid-containing protein; Bone gamma carboxyglutamate (gla) protein; OTTHUMP00000016586; ucOC

• Clonality:

  Monoclonal, Recombinant

• Clone:

  10A7

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Signal Transduction; Stem Cells

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  WB 1:100-1:500

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  11 kDa

• Observed Molecular Weight:

  22 kDa

• Isotype:

  IgG, κ