Recombinant GSK3β Monoclonal Antibody

• Background:

  The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Abbreviation:

  GSK3β

• UniProt:

  P49841

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human GSK3β protein

• Target:

  GSK3B; gsk-3β; Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3beta isoform; Serine/threonine-protein kinase GSK3B; glycogen synthase kinase-3 beta

• Clonality:

  Monoclonal, Recombinant

• Clone:

  7C10

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Neuroscience; Signal Transduction; Stem Cells; Cardiovascular; Cancer; Metabolism

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  WB 1:2000-1:10000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  47 kDa

• Observed Molecular Weight:

  47 kDa

• Isotype:

  IgG, κ