Recombinant PI3-Kinase p110α Monoclonal Antibody

• Background:

  Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns (4,5) P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.

• Abbreviation:

  PI3-Kinase p110α

• UniProt:

  P42336

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human PI3-Kinase p110α protein

• Target:

  CWS; PIK3CA; CLOVE; CWS5; MCAP; MCM; MCMTC; PI3K; PI3K-alpha;5 bisphosphate 3 kinase 110 kDa catalytic subunit alpha;5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha;5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha;5-bisphosphate 3-kinase catalytic subunit alpha isoform; caPI3K; MGC142161; MGC142163; p110 alpha; p110alpha; Phosphatidylinositol 3 kinase catalytic 110 KD alpha; Phosphatidylinositol 3 kinase catalytic alpha polypeptide; Phosphatidylinositol 4; Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha; Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform; Phosphatidylinositol-4; Phosphoinositide 3 kinase catalytic alpha polypeptide; Phosphoinositide 3-kinase alpha; Phosphoinositide-3-kinase catalytic alpha polypeptide; PI3 kinase p110 subunit alpha; PI3Kalpha; PI3KC A; PI3-kinase subunit alpha; PIK3C A; PK3CA; PtdIns 3 kinase p110; PtdIns-3-kinase subunit alpha; PtdIns-3-kinase subunit p110-alpha; Serine/threonine protein kinase PIK3CA; PIK3CA H1047R

• Clonality:

  Monoclonal, Recombinant

• Clone:

  7C1

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Signal Transduction; Cancer; Immunology

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  WB 1:2000-1:10000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  124 kDa

• Observed Molecular Weight:

  110 kDa

• Isotype:

  IgG, κ